Updated Evidence-Based Treatment Algorithm in Pulmonary Arterial Hypertension
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چکیده
منابع مشابه
Updated evidence-based treatment algorithm in pulmonary arterial hypertension.
Uncontrolled and controlled clinical trials with different compounds and procedures are reviewed to define the risk-benefit profiles for therapeutic options in pulmonary arterial hypertension (PAH). A grading system for the level of evidence of treatments based on the controlled clinical trials performed with each compound is used to propose an evidence-based treatment algorithm. The algorithm ...
متن کاملA Treatment Algorithm for Pulmonary Arterial Hypertension
Nazzareno Galiè, MD Department of Experimental, Diagnostic and Specialty Medicine-DIMES Bologna University Hospital Bologna, Italy The treatment algorithm for pulmonary arterial hypertension (PAH) represents graphically a sequence of operations that are needed for the management of patients. The treatment algorithm includes different types of recommendations with varying degrees of scientific e...
متن کاملPulmonary arterial hypertension: therapeutic algorithm.
The numerous controlled clinical trials performed recently in pulmonary arterial hypertension (PAH) can allow us to abandon a clinical-based treatment strategy and adopt an evidence-based therapy. The treatment algorithm is restricted to patients in NYHA class III or IV. The different treatments have been evaluated mainly in sporadic, idiopathic PAH and in PAH associated with scleroderma or to ...
متن کاملTreatment of pulmonary arterial hypertension.
the authors reply: Arias et al. correctly note that diabetes is an independent risk factor for congestive heart failure. Data from the Cardiovascular Health Study have also shown a significant independent relationship between diabetes and the development of congestive heart failure1; most cases of heart failure in that cohort were associated with a normal or near-normal ejection fraction — that...
متن کاملTreatment of pulmonary arterial hypertension.
Patients with pulmonary arterial hypertension (PAH) must be referred to expert centers (reference center and competences centers in the French PAH network). Despite progresses in the knowledge of PAH pathophysiology, it is still a devastating disease needing an aggressive approach of therapy to improve long-term outcomes. The target of current therapies is endothelial dysfunction of pulmonary a...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2009
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2009.04.017